Metabolic Ledger

The GLP-1 Price Index

What a month of GLP-1 medication actually costs in cash, tracked over time. We take the median monthly cash price across a fixed basket of US providers and rebase it to 100, so you can see the market move — not just a single sticker price.

Latest period: June 2026 · refreshes on the 1st of each month. Cite, embed, or download →

All-GLP-1 index
100.0
median $339/mo · 8 priced constituents
Month over month
Baseline month — deltas begin next update.
Quarter over quarter
Needs three months of history.

Index over time

History starts this month — every series is rebased to 100 at June 2026. The trend line fills in with each monthly update.

Index (baseline = 100)9999100101101Jun 26
All GLP-1 (monthly cash) Compounded (all) Compounded semaglutide Compounded tirzepatide Brand (NovoCare / LillyDirect)

Latest values (June 2026)

SeriesIndexMedian / moMean / moConstituentsMoM
All GLP-1 (monthly cash)100.0$339$3488
Compounded (all)100.0$313$3214
Compounded semaglutide100.0$253$2532
Compounded tirzepatide100.0$389$3892
Brand (NovoCare / LillyDirect)100.0$374$3744

What’s in the basket

The distinct monthly medication cash prices that feed the index this period. Manufacturer prices (NovoCare, LillyDirect) appear once even though several of our guides cite them. Membership/program fees and first-month promos are excluded.

Price conceptTypeDrugPriceSource
NovoCare Wegovy injectable standard monthly pricebrandsemaglutide$349/monthlink
LillyDirect Zepbound 2.5mg starter monthly pricebrandtirzepatide$299/monthlink
LillyDirect Zepbound 5mg monthly pricebrandtirzepatide$399/monthlink
LillyDirect Zepbound 7.5mg and above monthly pricebrandtirzepatide$449/monthlink
Eden compounded semaglutide ongoing monthly pricecompoundedsemaglutide$209/monthlink
Henry Meds compounded injectable semaglutide recurring monthly pricecompoundedsemaglutide$297/monthlink
Eden compounded tirzepatide ongoing monthly pricecompoundedtirzepatide$329/monthlink
Henry Meds compounded injectable tirzepatide recurring monthly pricecompoundedtirzepatide$449/monthlink

How the index is built

  • Constituent= one distinct price concept (e.g. “Henry Meds compounded tirzepatide, recurring monthly”). A constituent’s value is the median across however many of our guides cite it, so a manufacturer price quoted in several articles still counts once.
  • Basket = monthly medication cash prices only. Membership/program fees, first-month promos, and one-time charges are stored but excluded, so the index reflects the cost of the drug itself.
  • Index value= 100 × (this period’s median ÷ the earliest period’s median) for each series. A series is only published once it has at least two constituents.
  • Cadence— prices are re-checked on the 1st of each month against each provider’s own live page. The methodology page covers source selection and review.

The index is an estimate of typical advertised cash prices, not a quote. Your actual cost depends on dose, insurance, and provider. See our cost & access guides for individualised figures.

Use the data

The index is free to cite, embed, and download under CC BY 4.0. See cite, embed, or download for the embed code, citation format, and the JSON/CSV endpoints.